I have an image I need to edit, removing pixelation on multiple sides to give "clean" edges. It is a full color image and I don't want/need to convert the image to a vector. I have created a rectangle, converted to path, raised the shape to the top, selected both this shape and the image, used Path>Difference. I then draw a rectangle over the image and shape, drop down one level. Select all and do Object>Clip>Set. That works fine, however when I then go to do another edge and follow the same process, the first clip disappears.

I know Inkscape only allows one clip to be active at a time, however cannot work out how to remove multiple sections of the image any other way. I have tried masking however that did not achieve the desired result.

Thanks

I'd try using the image as a pattern fill, then use path operations (booleans) to remove various areas.

An example file with annotations would be helpful.

You can put as many shapes into one compound path (Path->Combine) to use as a Clipping path and edit these components with the Node tool:

For some reason "Clip->Set inverse" don´t work here on macOS.

Thanks @TylerDurden & @Polygon, will try both of these and see if they solve my problem. As always thanks for your awesome help :)